Funding opportunities
Open and upcoming programs from Canadian funders and US federal grants (Grants.gov). Deadlines first, then rolling intakes.
Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
This NOFO is issued during a period of accelerating development, validation, and adoption of human new approach methodologies (NAMs). Accordingly, it has two integrated priorities for NIH-funded HIV/AIDS research: (1) implementation of a NAMs-enabled stewardship framework, including optional HIV-relevant human in vitro testing support and pilot benchmarking activities, to reduce or replace specific pathogen free (SPF) in vivo model use where scientifically appropriate without compromising rigor, reproducibility, or translational relevance; and (2) support for high-quality SPF colony resources for studies in which well-characterized in vivo models remain scientifically necessary. Under the NAMs-enabled component, required elements include: (1) integration of a NAMs triage and consultation service within request intake and allocation workflows to identify NAM-feasible studies and document reductions or replacements in in vivo use; and (2) establishment of a formal referral pathway to NAM centers as well as human tissue and other human science based resources to facilitate collaborative HIV-relevant human NAM development, benchmarking, and refinement. Applicants may also propose optio Awards range from $212,004 to $2,725,311.
Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
National Institutes of Health · Deadline not published
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to continue to support the Radiation Oncology-Biology Integration Network (ROBIN) with applications from both new and renewing investigators. This network model will sustain an agile and effective national radiation oncology infrastructure that collectively addresses critical hypothesis-based translational research on the biological basis of responses in cancer patients who undergo radiation treatments. ROBIN supports a collaborative national research network focused on understanding how tumors and normal tissues change biologically during radiation therapy. Because radiation can dynamically alter molecular targets over the course of treatment, the network seeks to generate foundational knowledge that can improve radiation-based cancer care and identify new opportunities for combining radiation with drugs and other therapies. Through multidisciplinary, longitudinal studies, ROBIN centers collect and analyze biospecimens and multimodal data before, during, and after standard-of-care radiation therapy. This work is designed to reveal mechanisms of response, resistance, and toxicity; identif
National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional)
National Institutes of Health · Deadline not published
This Notice of Funding Opportunity (NOFO) encourages grant applications for National Centers for Biomedical Imaging and Bioengineering (NCBIB). NCBIB are national resource centers for conducting research and development on new technologies that are driven by the needs of basic, translational, and/or clinical researchers. NCBIB also make their technologies available to other investigators, train members of the research community in the use of the technologies and disseminate the technologies broadly.
Limited Competition: NIMHD Initiative for Improving American Indian and Alaska Native Cancer Outcomes (U19 - Clinical Trial Optional)
National Institutes of Health · Deadline not published
The purpose of this Notice of Funding Opportunity (NOFO) is to support research that addresses the prevention, diagnosis, and treatment of cancers among American Indians and Alaska Natives (AI/AN), particularly those living in rural communities. The research objectives target overall cancer incidence and mortality, with the goal of making findings applicable and impactful in improving cancer outcomes in AI/AN patients and their families. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
Clinical and Translational Science Award
National Institutes of Health · Deadline not published
The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the reissuance of the CTSA Notice of Funding Opportunity (NOFO) is to support a CTSA Hub that provides an integrated research and training environment for clinical and translational science and catalyzes the development, demonstration, and dissemination of methods and technologies that dramatically improve efficiency and quality across the translational research spectrum. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. This is a Forecast that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section fo
Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant for the Clinical and Translational Science Awards Program
National Institutes of Health · Deadline not published
The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the reissuance of the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program Notice of Funding Opportunity (NOFO) is to support institutional programs that prepare predoctoral and postdoctoral research training in clinical and translational science. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Se
Limited Competition: Research Education Program for the Clinical and Translational Science Awards Program
National Institutes of Health · Deadline not published
The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the reissuance of the Research Education Program for the CTSA Program Notice of Funding Opportunity (NOFO) is to support educational activities that complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral and clinical research needs. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review pro
Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science
National Institutes of Health · Deadline not published
The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded CTSA Program Hubs. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NI
The Next Generation of the Clinical and Translational Science Awards Program Trial Innovation Network
National Institutes of Health · Deadline not published
The Clinical and Translational Science Awards Program Trial Innovation Network (TIN) is a collaborative initiative aimed at addressing critical roadblocks in the design and implementation of multi-center clinical trials. The goal of the TIN is to execute trials better, faster, and more cost-efficiently, as well as serve as a national laboratory to study, understand, and innovate the process of conducting multi-center clinical trials. The purpose of the issuance of the Next Generation of the TIN Notice of Funding Opportunity (NOFO) is to advance the science of clinical trials by developing and implementing innovative solutions to address challenges at the clinical trial and trial network levels. Topics of interest include, but are not limited to, safety monitoring tools and resources, trial leader training and mentorship, digital health technologies, genomic capacity, and disease progression modeling. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. This is a Forecast that will invite applications from all eligible organizations to apply. P
Fiscal Year (FY) 2027 State and Regional Primary Care Association (PCA) Cooperative Agreements
Health Resources and Services Administration · Deadline not published
The purpose of the Fiscal Year (FY) 2027 State and Regional Primary Care Association (PCA) program is to develop and deliver technical assistance (TA) that supports existing and potential Health Center Program award recipients and look-alikes (LALs), hereafter referred to as health centers, both directly and collaboratively with other HRSA-funded TA programs. PCAs will improve the health of medically vulnerable individuals and communities by: Increasing access to high-quality preventive and primary health care services. Improving chronic disease prevention and management to enhance the overall health of communities. Recruiting, retaining, and training a health center workforce. Preparing for, responding to, and recovering from emergent health events. Implementing payer strategies, including value-based care delivery, to ensure high functioning, financially sustainable health centers. Accelerating data-informed improvements to improve operations and clinical quality. Awards range from $790,000 to $4,900,000.
EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations (FEC)
U.S. National Science Foundation · Deadline 2027-01-26
The Established Program to Stimulate Competitive Research (EPSCoR) is designed to fulfill the mandate of the National Science Foundation (NSF) to promote scientific progress nationwide. EPSCoR eligibility status is yearly updated and reported in the EPSCoR website (see EPSCoR eligibility). Through this program, NSF establishes partnerships with government, higher education, and industry that are designed to affect sustainable improvements in a jurisdiction's research infrastructure, Research and Development (R&D) capacity, and hence, its R&D competitiveness. The FEC program (formerly known as “EPSCoR Track-2 program”) builds interjurisdictional collaborative teams of EPSCoR investigators in Science, Technology, Engineering, and Mathematics (STEM) focus areas consistent with the current National Science Foundation Strategic Plan . Projects are investigator-driven and must include researchers from at least two EPSCoR eligible jurisdictions with complementary expertise and resources necessary to address challenges, which neither party could address as well or as rapidly independently. FEC projects have a comprehensive and integrated vision to drive discovery and build sustainable STEM Awards range from $1,000,000 to $1,500,000.
National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-01-26
This Notice of Funding Opportunity (NOFO) is for support of National Centers for Cryoelectron Tomography (CryoET) to provide nationwide access to advanced cryoET instrumentation and technical support, and to assist investigators in acquiring the skills needed to perform cryoET studies.
HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)
National Institutes of Health · Deadline 2027-01-26
The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewed network will include several individual research projects supported by one central Coordination Center. The goal of the network is to test new and improved approaches for people who have both chronic pain (CP) and opioid use disorder (OUD). These approaches should lead to meaningful improvements in how health systems deliver care. The network will be part of the NIH’s Helping to End Addiction Long-term (HEAL®) Initiative to speed the development and implementation of scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative will bolster research across NIH to (1) improve treatment and prevention of opioid misuse and OUD and (2) enhance pain management.
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-01-26
The National Institutes of Health (NIH) intends to renew the Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) research network. This renewal consists of individual research projects, which will be supported by a single Coordination Center. This network is intended to test new innovations that integrate evidence based treatments for chronic pain (CP) and opioid use disorder (OUD). This research will characterize or modify factors that impact wide-scale adoption and sustained use of effective treatments at this intersection. The network will be part of the NIH’s Helping to End Addiction Long-term (HEAL®) Initiative to speed the development and implementation of scientific solutions to the national opioid public health crisis. The NIH HEAL Initiative will bolster research across NIH to (1) improve treatment and prevention of opioid misuse and OUD and (2) enhance pain management. This notice of funding opportunity (NOFO) seeks applications for a single Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center. The BEACON Center will provide overall network coordination support; research education activities to build capacity at the inte
NIOSH Miner Safety and Health Training Program - Western United States – U60
Centers for Disease Control and Prevention - ERA · Deadline not published
Background Despite advances in technology and improvements in work environments, mining remains one of the most challenging and hazardous occupations in the United States. The industry continues to experience a fatality rate nearly three times higher than the national average for all industries, according to the U.S. Bureau of Labor Statistics (BLS). Public MSHA data show that in 2025, the U.S. mining sector employed 372,899 workers and operated 12,600 mining sites nationwide. That year, the industry reported 33 fatalities, and the fatality rate for 2015–2025 ranged between 8 and 16 per 100,000 FTE. MSHA reported that the overall mining industry's all-injury rate reached 1.74 injuries per 200,000 hours worked in 2025. Purpose The purpose of this Notice of Funding Opportunity (NOFO) is to enhance the quality, relevance, and availability of health and safety training for miners in the Western United States. Availability includes training frequency, geographic access, delivery methods and partnerships, and the cultural and educational appropriateness of materials. This NOFO is intended to complement, not duplicate existing MSHA, OSHA, and state-supported training programs and to addre Awards up to $250,000.
Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-01-27
The purpose of the Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) award is to support federally recognized American Indian/Alaska Native (AI/AN) Tribes, Tribal colleges and universities, Tribal health programs, or Tribal organizations(collectively, eligible Tribal entities) to establish Institutional Review Boards (IRBs) or enhance the capacity of existing Tribal IRBs.
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-01-27
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program aims to promote broad participation in the biomedical research ecosystem by supporting resource limited organizations to conduct research, enhance the research environment, and increase sponsored programs administration capacity.This program intends to support eligible, domestic organizations with limited research resources and few biomedical doctoral students. Awards up to $500,000.
Diabetes Research Centers (P30 Clinical Trial Optional)
National Institutes of Health · Deadline 2027-01-27
This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, multidisciplinary collaboration, and effectiveness of ongoing research in Diabetes Research Center topic areas. By providing shared access to specialized technical resources (research cores) and supporting a Pilot and Feasibility Program (P&F), DRCs are intended to create an environment that provides the capability for accomplishments greater than those that would be possible by individual research project grant support alone. New Center programs that bring in diverse perspectives, propose unique scientific themes, or provide innovative resources are encouraged. Emphasis will be placed on Center programs that propose enhanced synergies with other NIDDK-funded programs as well as providing a rich mentoring environment for future diabetes researchers. Awards up to $1,000,000.
Specialized Alcohol Research Centers (P50 Clinical trial Optional)
National Institutes of Health · Deadline 2027-01-27
The National Institute on Alcohol Abuse and Alcoholism (NIAAA) supports a broad-based Alcohol Research Centers program to foster and conduct interdisciplinary, collaborative research on alcohol misuse, Alcohol Use Disorder (AUD), and alcohol-related problems, and other health-related consequences across the lifespan. The NIAAA Centers Program provides leadership in research, and research methodology development on a wide variety of topics relevant to the Institute's mission. The focus of the NIAAA Centers program should be on generating a critical mass of researchers in a given understudied and/or innovative topic area relevant to the NIAAA mission with an emphasis on interdisciplinary coordination and cooperation among independent researchers and development and mentorship of young investigators. A center must contribute more to the alcohol field than the sum of its parts. Topics include but are not limited to, the nature, etiology, genetics, diagnosis, treatment, and prevention of alcohol misuse, AUD, alcohol-related end-organ diseases, and their biomedical, psychosocial, and population health consequences across the lifespan. Centers are also major contributors to the developmen Awards up to $1,150,000.
Methodology, Measurement, and Statistics (MMS)
U.S. National Science Foundation · Deadline 2027-01-28
The Methodology, Measurement, and Statistics (MMS) Program is an interdisciplinary program in the Directorate for Social, Behavioral, and Economic Sciences that supports the development of innovative analytical and statistical methods and models for those sciences. MMS seeks proposals that are methodologically innovative, grounded in theory, and have potential utility for multiple fields within the social, behavioral, and economic sciences. As part of its larger portfolio, the MMS Program partners with a consortium of federal statistical agencies to support research proposals that further the production and use of official statistics. The MMS Program provides support through a number of different funding mechanisms. The following mechanisms are addressed in this solicitation: Regular Research Awards Awards for conferences and community-development activities Doctoral Dissertation Research Improvement (DDRI) Grants Research Experience for Undergraduates (REU) Supplements MMS also supports Faculty Early Career Development (CAREER) awards. Please see the CAREER Program Web Site for more information about this activity.