Funding opportunities
Open and upcoming programs from Canadian funders and US federal grants (Grants.gov). Deadlines first, then rolling intakes.
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications to support the validation of molecular/cellular/imaging markers (referred to as "markers" or "biomarkers") and assays for cancer detection, diagnosis, prognosis, monitoring, and prediction of response or resistance to treatment, as well as markers for cancer prevention and control. The applicants have the option of submitting either a biphasic UH2/UH3 (Developmental Cooperative Agreement Phase I/Developmental Cooperative Agreement Phase II) application for 5 years or a monophasic standalone UH3 (Developmental Cooperative Agreement Phase II) application for 3 years to support clinical validation of established assays. The UH2 phase of this NOFO will support analytical validation of assays for the markers, which must be achieved within 2 years before assays may undergo clinical validation. The UH3 phase of this NOFO will support clinical validation of analytically validated assays for up to 3 years using well-annotated biospecimens from retrospective or prospective clinical trials or studies. Investigators applying for UH2/UH3 must address both UH2 and UH3 phases, and propose
Establishing a Research Network to Guide Foundational Research on Human Consciousness
National Institutes of Health · Deadline not published
This Funding Opportunity will establish the NIH Blueprint for Neuroscience Research Network to Guide Foundational Research on Human Consciousness , leveraging a trans-NIH collaboration of 14 Institutes, Centers, and Offices dedicated to reducing the burden of nervous system disorders. Consciousness is central to numerous serious biomedical conditions, including coma, delirium, dementia, traumatic brain injury, stroke, sleep disorders, metabolic disorders, and seizures - conditions central to NIH's biomedical mission. Yet the neural mechanisms that support conscious states remain insufficiently understood, limiting clinicians’ ability to diagnose and treat patients effectively. Advancing foundational science on human consciousness will strengthen clinical decision-making and improve outcomes for patients with costly and hard-to-treat neurologic and systemic illnesses by: Detecting consciousness in minimally responsive patients to guide prognosis, treatment, and ethical decisions (e.g., organ harvesting). Improving understanding of consciousness in Alzheimer’s disease, related dementias, and delirium. Investigating altered states in mental disorders to inform treatments. Identifying
NIOSH Robotics and Intelligent Mining Technology and Workplace Safety Research (U60)
Centers for Disease Control and Prevention - ERA · Deadline not published
Purpose This NOFO supports applied research to advance automation, robotics, and intelligent mining systems that improve safety and health in U.S. mining operations. Projects should deliver field-ready solutions that strengthen communication, self-escape, refuge performance, and overall safety through modern autonomy, sensing, and decision-support technologies. Background Mining remains hazardous. In 2025, MSHA recorded 33 fatalities, including powered-haulage and machinery incidents. Early 2026 data show continued roof and rib failures and pressure-vessel events. Although the 2025 injury rate reached a historic low, gaps persist in emergency communication reliability, low-visibility self-escape, and refuge performance. Advances in robotics and intelligent systems offer potential for rapid assessment, resilient communications, and improved decision-making. Approach The Miner Health Program, 2020–2030 Strategic Agenda provides a long term framework for improving miner health and well being through integrated research, evaluation, and community engagement. This cooperative agreement aligns with that agenda by supporting research in robotics and intelligent mining to reduce hazardous Awards up to $2,000,000.
A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO)
U.S. National Science Foundation · Deadline 2027-02-09
The National Science Foundation (NSF) and the National Institutes of Health (NIH) are interested in proposals that will propel our understanding of the biomedical research enterprise by drawing from the scientific expertise of the science of science policy research community. NSF promotes the progress of science by maintaining the general health of research and education across all fields of science and engineering. The Social, Behavioral and Economic Sciences (SBE) Directorate within NSF supports basic research on people and society. The SBE sciences focus on human behavior and social organizations; how social, economic, political, cultural and environmental forces affect the lives of people from birth to old age; and how people in turn shape those forces. SBE's Science of Science: Discovery, Communication and Impact Program (SoS:DCI) supports research designed to advance the scientific basis of science and innovation policy. The NIH is the U.S. federal agency charged with supporting biomedical research in the U.S. The National Institute of General Medical Sciences (NIGMS) within the NIH supports basic biomedical research that increases understanding of biological processes and la Awards range from $100,000 to $250,000.
Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-02-09
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute invites applications to the Carcinogen Hazard Assessment Monographs Program (CHAMP) Initiative . NCI seeks meritorious proposals to critically and systematically evaluate the scientific evidence on carcinogenic hazards to humans. Identifying potential carcinogens is essential for guiding and advancing cancer research, as well as informing cancer control and prevention efforts. Awards range from $700,000 to $700,000.
International Research Scientist Development Award (IRSDA)
National Institutes of Health · Deadline not published
This initiative will provide salary and research support to advanced U.S. postdoctoral researchers and junior faculty for intensive mentored research and career development activities focused on biomedical, behavioral, and/or clinical research in low- and middle-income countries (LMICs). Proposals will leverage special opportunities not present in the U.S. and result in generalizable knowledge applicable to the health of U.S. and LMIC populations. Recipients will be required to spend significant time at the LMIC research site and receive mentoring from senior U.S. and LMIC researchers. This experience will provide recipients with a deep understanding of the local research environment and foster collaborative relationships necessary to develop competitive independent NIH research proposals. A sustained period of research career development will enable recipients to become global leaders in their fields, serve as mentors to the next generation of investigators, and strengthen international networks that support NIH research investments.
Science of Learning and Augmented Intelligence (SL)
U.S. National Science Foundation · Deadline 2027-02-10
Science of Learning and Augmented Intelligence (SL) supports potentially transformative research that develops basic theoretical insights and fundamental knowledge about principles, processes and mechanisms of learning, and about augmented intelligence — how human cognitive function can be augmented through interactions with others or with technology, or through variations in context. The program supports research addressing learning in individuals and in groups, across a wide range of domains at one or more levels of analysis, including molecular and cellular mechanisms; brain systems; cognitive, affective and behavioral processes; and social and cultural influences. The program also supports research on augmented intelligence that clearly articulates principled ways in which human approaches to learning and related processes, such as in design, complex decision-making and problem-solving, can be improved through interactions with others or through the use of artificial intelligence in technology. These could include ways of using knowledge about human functioning to improve the design of collaborative technologies that have the capacity to learn to adapt to humans. For both aspec
Silvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)
National Institutes of Health · Deadline 2027-02-10
This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance communication, collaboration, and effectiveness of ongoing research related to digestive and/or liver diseases within the NIDDK's mission. DDRCCs are based on the core concept, whereby shared resources aimed at fostering productivity, synergy, and new research ideas among the funded investigators are supported in a cost-effective manner. Each proposed DDRCC must be organized around a central theme that reflects the focus of the digestive or liver diseases research of the Center members. The central theme must be within the primary mission of the NIDDK, and not thematic areas for which other NIH Institutes or Centers are considered the primary source of NIH funding. Awards up to $750,000.
Multimodal AI to Accelerate Precision Medicine for Type 1 Diabetes (U01- Clinical Trials Not Allowed)
National Institutes of Health · Deadline not published
Type 1 diabetes (T1D) is a complex disease involving interactions among many different cell types, tissues, organs and biological processes. Genetics, the environment, and lifestyle all play a role in disease development and progression. Over the past two decades, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has supported major T1D research consortia covering basic, translational, and clinical research. Each consortium has focused on different aspects of T1D, such as specific organs, stages of disease or clinical outcomes. Together, these consortia have collected large longitudinal and multimodal datasets using standardized protocols and coordinated studies. While individual consortia have improved our understanding of specific areas, combining their work offers a rare opportunity to see how different biological processes interact to drive T1D development and progression. This integrated view can answer fundamental questions about T1D biology that cannot be answered using individual datasets or studies alone. Recent advances in artificial intelligence (AI) now make it possible to integrate these complementary datasets and study T1D across various tis
Public Health Crisis Response Cooperative Agreement
Centers for Disease Control - OPHPR · Deadline 2027-02-11
CDC seeks to enhance the nation’s ability to rapidly mobilize, surge, and respond to public health emergencies (PHEs) as identified by CDC by establishing a roster of approved but unfunded (ABU) applicants that may receive rapid funding to respond to PHEs of such magnitude, complexity, or significance that they would have an overwhelming impact upon, and exceed resources available to, the jurisdictions. Applicants will undergo an objective merit review process, and entities that successfully meet the requirements for approval will be placed on the ABU list. CDC will use this ABU list for emergencies that require federal support to effectively respond to, manage, and address identified public health threats. CDC will make funding related to this NOFO available once it has determined a public health emergency exists or is considered imminent and will be contingent upon the availability and stipulations of appropriations. CDC will provide additional guidance and information to those on the ABU list when this NOFO is funded. Since this NOFO is designed to collect applications prior to a PHE, applicants are encouraged to submit work plans and budgets that demonstrate their ability to re Awards range from $50,000 to $5,000,000.
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-02-11
The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie: 1. Phenotypes associated with addictive behaviors and/or vulnerability to distinct stages along the substance use disorders (SUD) trajectory (e.g. initial/acute use, escalation of use, acquisition of tolerance, dependence, uncontrolled use, abstinence and relapse or recovery); 2. Behaviors associated with SUD (e.g. impulsivity, novelty seeking, delayed discounting, and other genetically-associated phenotypes); and 3. Comorbidities that demonstrate genetic correlations with phenotypes and behaviors linked with SUD (e.g. anxiety, stress, poor maternal care, social defeat, and other paradigms). Applications may examine any type of genomic variant, including single nucleotide variants (SNVs), indels, large and small structural variants, and all types of mobile DNA. NIDA encourages applications that take genomics, multi-omics, and/or data-based approaches that integrate multi-level omics data, delineate gene networks, and/or uncover the function of known or newly discovered genetic or epigenetic variants. Other areas of interest include genomics analysis at
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-02-11
Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity within precisely localized brain structures, enabling high-impact human neuroscience investigations. This NOFO seeks exploratory research projects, from newly formed or established multi-disciplinary teams, to understand how dynamic activity of single cells and ensembles of neurons in spatially organized networks gives rise to the internal states we experience as sensations, perceptions, emotions, thoughts, and memories, and to observable motor and social behaviors. The research should be proposed as exploratory research and planning activities to establish feasibility and early-stage development that, if successful, would support, enable, and/or lay the groundwork for a potential, subsequent research project grant applications using invasive neural recording and stimulation technologies in the human brain. Projects should maximize opportunities to conduct innovative in vivo human neuroscience research made available by direct access to the brain from invasive surgical procedures. Projects should employ approaches guided by specified theoretical constructs an Awards up to $700,000.
Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network Biospecimen Banks (NCTN Biobanks) and the NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) (U24 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-02-11
This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. Through this limited competition Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications to support continuation of two biospecimen banking resources. The National Clinical Trials Network (NCTN) Biospecimen Banks (NCTN Biobanks) support the NCI-funded NCTN and the Community Oncology Research Program (NCORP), and The Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) supports the Experimental Therapeutics Clinical Trials Network (ETCTN) and other NCI-supported early phase and experimental clinical trials. The objective is to maintain these national resources for the collection, processing, storage, and distribution of high-quality, clinically annotated human biospecimens. The goal of these resources is to ensure the availability of biospecimens from pa
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-02-11
The National Library of Medicine (NLM) invites applications for innovative predoctoral and postdoctoral training programs that prepare the next generation of researchers in biomedical informatics, data science, and artificial intelligence/machine learning (AI/ML). NLM emphasizes cutting-edge, forward-looking training experiences that equip trainees to address complex health and biomedical challenges through advanced computational approaches. Applications may propose the creation of new training programs or the renewal of existing NLM-supported programs. These programs are designed to meet the growing demand for researchers with deep expertise in biomedical computing, data science, and AI/ML, with clear relevance to health and biomedical research. Recognizing the inherently interdisciplinary nature of these fields, NLM seeks programs that integrate methods and perspectives across disciplines to advance biomedical informatics, data science, and AI/ML. Awards range from $500,000 to $775,000.
Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-02-11
The purpose of this notice of funding opportunity (NOFO) is to support research and/or preclinical development of highly efficacious vaccines against malaria - one of the deadliest mosquito-borne diseases - by capitalizing on recent technological innovations, particularly in structure-based immunogen design, improved formulations, and combination vaccines. The goal is to achieve long-lasting, highly effective protection that can save lives, strengthen public health security in the United States, and serve as a model for, or are potentially effective against, other mosquito-borne diseases.
Digital Health Technology and Reciprocal Innovation to Improve Clinical and Public Health Outcomes
National Institutes of Health · Deadline not published
This initiative will support research on the development, validation, feasibility, and effectiveness of innovative digital health interventions or tools (including mobile health) specifically suited for underserved settings in the U.S. and globally. Research should utilize new or emerging technologies, platforms, systems, and/or analytics to address high priority health problems, expand the evidence base for the use of digital health technology to improve clinical and public health outcomes, and strengthen research collaborations between U.S. and low- and middle-income country (LMIC) researchers. Applications must include reciprocal innovation methodologies – bidirectional and iterative exchange of ideas, resources, and innovation approaches to address shared health challenges in the U.S. and a LMIC. Through this utilization of unique data, environments, and populations in domestic and international contexts, awards will maximize generalizable knowledge produced and optimize potential benefit to U.S. and LMIC populations.
EMERGING FRONTIERS IN RESEARCH AND INNOVATION (EFRI-2026/27): Wave-Based Computing ( EFRI-WBC)
U.S. National Science Foundation · Deadline 2027-02-11
The Emerging Frontiers in Research and Innovation (EFRI) program serves a critical role in helping the NSF Directorate for Engineering focus on important emerging areas in a timely way. The EFRI program invests in potentially transformative ideas that offer the opportunity for significant shifts in foundational engineering knowledge. EFRI-funded research must have strong potential for long-term impact on strategic technology priorities and/or national science and technology (S&T) missions identified in the Administration's Fiscal Year (FY) 2028 Research and Development (R&D) Budget Priorities Memorandum. Such impacts need not be fully realized within the duration of the research period; however, proposers are expected to articulate how a proposal is use-inspired and may lay the foundations for stated priorities. This EFRI solicitation leverages a portfolio of both two-year EArly-concept Grants for Exploratory Research (EAGER) awards and larger four-year awards in response to Science: A New Golden Age , which calls for a more flexible set of funding mechanisms that match the scientific challenges they seek to address. The EFRI Wave-Based Computing (WBC) solicitation will support fou
Limited Competition: Institutional Mentored Research Career Development Program for the Clinical and Translational Science Awards Program
National Institutes of Health · Deadline not published
The purpose of the Congressionally mandated Clinical and Translational Science Award (CTSA) Program is to accelerate the translation of scientific discoveries into treatments, diagnostics, and health interventions that improve patient and public health by funding and coordinating a national network of academic medical centers that provide the infrastructure, expertise, training, and collaboration needed to move discoveries from the laboratory into clinical practice and community health. The purpose of the reissuance of the Institutional Mentored Research Career Development Program for the CTSA Program Notice of Funding Opportunity (NOFO) is to support institutional programs that prepare later-stage postdoctoral fellows and junior faculty committed to independent clinical and translational science careers for timely advancement and sustained research engagement. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Elig
Capacity Building for Global, Regional, and National Immunization Programs
Centers for Disease Control-GHC · Deadline not published
This award aims to strengthen immunization programs in priority countries so they can better prevent, control, and eliminate/eradicate vaccine-preventable diseases (VPDs) like polio, measles, and rubella, reduce illness and death from these diseases, and respond to emerging global health threats. The Recipient will build stronger systems in priority countries to prevent, detect, and respond to VPDs. This includes improving immunization services, strengthening VPD surveillance, and expanding the capacity to prepare for and manage outbreaks. The Recipient will also create and carry out targeted approaches to reach high-risk groups who are un- or under-immunized. Additionally, the Recipient will promote long-term sustainability of immunization programs–such as supporting evidence-based decisions through National Immunization Technical Advisory Groups (NITAGs)–and enhance program evaluation to increase impact. The Recipient will manage and coordinate Pakistan's National Stop Transmission of Polio (NSTOP) program and assist countries facing polio outbreaks or at high risk for them. This agreement may also support other global health priorities aligned with CDC goals. Awards up to $120,000,000.
Informing global polio eradication efforts through innovative modeling approaches
Centers for Disease Control-GHC · Deadline not published
This NOFO will provide critical disease modeling to inform decision making on the development of strategies for cVDPV2 outbreak response, optimal surveillance upon global WPV eradication, and surveillance to detect containment breaches. It will also build capacity for a diverse public health workforce of statistical and mathematical modelers. Additionally, models will assess economic implications of outbreak response and surveillance strategies, while developing workforce capacity for students in statistical and mathematical modeling for polio and other VPDs.