Funding opportunities
Open and upcoming programs from Canadian funders and US federal grants (Grants.gov). Deadlines first, then rolling intakes.
NIOSH Centers of Excellence for Total Worker Health® (U19)
Centers for Disease Control and Prevention - ERA · Deadline not published
PURPOSE NIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation. PRIORITY AREAS • High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies • Young workers, SMEs • Chronic disease • Mental health, stress • Substance use disorder • Artificial intelligence (AI), digital technologies This is a multi-component NOFO. COMPONENT STRUCTURE Percentages indicate maximum share of total budget. Overall Component (Required) Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects. Administration, Evaluation, and Emerging Issues Core (Required; up to 15%) Suppo Awards range from $500,000 to $1,400,000.
Fiscal Year 2026 Flood Mitigation Assistance
Department of Homeland Security - FEMA · Deadline 2027-02-26
The Flood Mitigation Assistance (FMA) grant program provides federal funds to states, U.S. territories, federally recognized tribal governments, and local governments. The goal is to reduce or eliminate the risk of repetitive flood damage to buildings and structures insured by the National Flood Insurance Program (NFIP) in participating communities. FMA funds a variety of flood mitigation activities to lower flood risk to policyholders and reduce the NFIP’s financial exposure.
Mid-Career Advancement (MCA)
U.S. National Science Foundation · Deadline 2027-03-01
The MCA program offers an opportunity for scientists and engineers at the mid-career stage (see restrictions under Additional Eligibility Information) to substantively enhance and advance their research program and career trajectory. Mid-career scientists are at a critical career transition stage where they need to advance their research programs to ensure long-term productivity and creativity but are often constrained by service, teaching, or other activities that limit the amount of time devoted to research. The MCA program provides protected time, resources, and the means to gain new skills through synergistic and mutually beneficial partnerships, typically at an institution other than the candidate's home institution. Partners from outside the Principal Investigator's (PI) own subdiscipline or discipline are encouraged, but not required, to enhance interdisciplinary networking and convergence across science and engineering fields. Research p rojects that envision new insights on existing problems or identify new problems made accessible with cutting-edge methodology or expertise from other fields are encouraged . A key component of a successful MCA will be the demonstration tha
Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-03-01
The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program supported Biobank to advance the program's mission of accelerating health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.All of Us partnered research studies are collaborative initiatives funded by a study sponsor external to All of Us to collect and add new data to the All of Us Researcher Workbench in accordance with All of Us" best practices. All of Us partnered research studies are open to the broad scientific community and require investigators to apply for and receive an X01 award under this announcement.This will enable longitudinal follow‐up and repeat sampling, and provide multiomic data (genomics, proteomics, metabolomics, and other high‐dimensional molecular profiles), integrated clinical, environmental, and life‐course data, infrastructure designed to support future clinical‐trial recruitment, and public‐private partnership pathways.This opportunity will enable researchers to conduct
Bridge2AI Network for AI Health Science
National Institutes of Health · Deadline not published
The purpose of this forecast is to inform the research community that the NIH Common Fund, along with its partner NIH Institutes, Centers, and Offices, is planning to issue a notice of funding opportunity (NOFO) to support the continuation of the Bridge2AI program. Stage 1 of the Bridge2AI program produced unique, large-scale, valuable, and open resource, AI-ready datasets and best practices that the scientific community can adopt. The second stage of the program will foster advances on two fronts: 1) Leverage the AI-ready datasets from Stage 1 to yield products that can address biomedical and behavioral research grand challenges, accelerate the discovery of new biological theories and rules, and advance understanding of biological and behavioral mechanisms of health and disease; 2) Create networks of multidisciplinary researchers to advance the science of AI science by developing necessary metrics and a framework to for trustworthy, reproducible and explainable AI-enabled biomedical and behavioral research. This forecast is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activ Awards range from $1,000,000 to $7,000,000.
Behavioral Health Integration Initiative
Indian Health Service · Deadline not published
The purpose of the BH2I program is to improve the physical, mental, social, and spiritual health of American Indian and Alaska Native (AI/AN) individuals by expanding integrated, coordinated behavioral health care. The program supports Tribal and Urban Indian Organization (UIO) health systems in delivering culturally responsive, trauma-informed services that integrate behavioral health with primary care, nutrition, exercise, and social, spiritual, and cultural supports. The goal is to improve access to comprehensive behavioral health services, promote early identification and treatment of mental health and substance use disorders, strengthen care coordination, and improve overall health outcomes and quality of life.
Zero Suicide Initiative
Indian Health Service · Deadline not published
The purpose of this program is to strengthen suicide prevention in Indian health systems by implementing the Zero Suicide framework through a comprehensive, culturally informed approach. The program supports Tribal health systems in building leadership, workforce capacity, systematic suicide risk identification, timely engagement and evidence-based treatment, continuity of care, and quality improvement to improve outcomes for American Indian and Alaska Native (AI/AN) individuals at risk for suicide.
NSF Scholarships in Science, Technology, Engineering, and Mathematics (S-STEM)
U.S. National Science Foundation · Deadline 2027-03-02
The main goal of the S-STEM program is to enable academically talented, low-income students to pursue successful careers in promising STEM fields. Ultimately, the S-STEM program seeks to increase the number of academically promising low-income students who graduate with an S-STEM eligible degree and contribute to the American innovation economy with their STEM knowledge. Recognizing that financial aid alone cannot increase retention and graduation in STEM, the program provides awards to institutions of higher education (IHEs) not only to fund scholarships, but also to adapt, implement, and study evidence-based curricular and co-curricular [a] activities that have been shown to be effective in supporting recruitment, retention, transfer (if appropriate), student success, academic/career pathways, and graduation in STEM. To be eligible, scholars must be domestic low-income students with academic ability, talent, or potential and demonstrated unmet financial need who are enrolled in an associate, baccalaureate, or graduate degree program in an S-STEM eligible discipline. Proposers must provide an analysis that articulates the characteristics and academic needs of the population of stu Awards range from $1,000,000 to $5,000,000.
Pathways to Enable Secure Open-Source Ecosystems (PESOSE)
U.S. National Science Foundation · Deadline 2027-03-02
The Pathways to Enable Secure Open-Source Ecosystems (PESOSE) program supports the translation of open-source science and engineering-focused research products into safe and sustainable ecosystems that address national and societal challenges. Open-source tools such as software, hardware, machine learning models, languages, and data platforms are designed to be shared as they are publicly-accessible and modifiable. These tools spark innovation in critical fields as varied as artificial intelligence (AI) and cloud computing, banking, healthcare, research, education, next-gen manufacturing, mobility, and National security (including cybersecurity). PESOSE supports the creation of managing organizations for these ecosystems, ensuring strong governance, distributed development, and broad user communities across academia, industry, and government. PESOSE also supports enhancements to the safety, security, and privacy of Open-Source Ecosystems (OSE) by addressing significant vulnerabilities, both technical and socio-technical, to improve the resistance of the ecosystem against threats. This solicitation seeks three types of proposals, allowing teams to propose specific activities to: 1)
Tribal Maternal, Infant, and Early Childhood Home Visiting Program: Development and Implementation Grants
Administration for Children and Families · Deadline not published
The Office of Early Childhood Development (ECD) within the Administration for Children and Families (ACF) will be soliciting applications for the Fiscal Year 2027 Tribal Maternal, Infant, and Early Childhood Home Visiting (MIECHV) Program: Development and Implementation Grants. Funds will support 5-year cooperative agreements between ACF and federally recognized Indian tribes (or a consortium of Indian tribes), tribal organizations, or urban Indian organizations interested in developing and implementing an evidence-based home visiting program serving expectant families and families with young children aged birth to kindergarten. Awards will support development and implementation of high-quality, culturally grounded, evidence-based home visiting services to American Indian and Alaska Native (AI/AN) children and families; implementation of performance measurement and continuous quality improvement systems; and development of early childhood systems. Home visiting programs are intended to promote outcomes such as improved maternal and prenatal health, infant health, and child health and development; reduced child maltreatment; improved parenting practices related to child development Awards range from $250,000 to $1,000,000.
Collaborative Centers in Children’s Environmental Health Research and Translation (P2C Clinical Trial Optional)
National Institutes of Health · Deadline not published
The overall goal of this NOFO is to solicit applications to create a national network of Children's Environmental Health Research Translation Centers (CEHRT). Through external collaboration with the children's environmental health community, the Centers will protect and improve children's health by developing and testing new scientific questions and public health interventions/strategies with an eye towards translation; and mentoring a pipeline of new investigators interested in translational Children's Environmental Health (CEH). The CEHRT Centers will serve as national leaders in CEH translational research and research methodology development, with a focus on creating actionable steps to move evidence-informed biomedical children's environmental health research findings to the wider community of practice to protect children from harm and to ensure a healthy future. The CEHRT program will also serve as a national research resource to support response efforts to emerging environmental exposures affecting children. Awards range from $500,000 to $750,000.
NIOSH National Center of Excellence for the Prevention of Childhood Agricultural Injury (U54)
Centers for Disease Control and Prevention - ERA · Deadline not published
The National Institute for Occupational Safety and Health (NIOSH) is committed to addressing a wide range of occupational health and safety hazards affecting those who work in the agriculture, forestry, and fishing (AgFF) sector. Children and adolescents ("youth") are consistently more likely to be fatally injured working in agriculture compared to other industries. While many steps have been taken to prevent youth injuries in AgFF work, there remains a need for a consistent national program to study and improve their safety, health, and well-being. This notice of funding opportunity (NOFO) will support a National Center of Excellence for the Prevention of Childhood Agricultural Injury and Illness ("the National Children's Center"). The National Children's Center will engage in high-quality research, education, outreach, and effective translation of scientific discoveries into practice for the benefit of youth living and working in AgFF communities. The activities of the National Children's Center will: Improve the collection and analysis of injury, illness, and fatality data for youth working and living in AgFF environments. Enhance research and practice to identify and address ga Awards up to $1,600,000.
NIOSH Centers for Agriculture, Forestry, and Fishing Safety and Health (U54)
Centers for Disease Control and Prevention - ERA · Deadline not published
The Agriculture, Forestry, and Fishing (AgFF) sector is essential to the safety, security, and economic stability of the U.S. because it produces the nation's food, fuel, and fiber. At the same time, AgFF workers experience some of the highest occupational fatality and non-fatal injury rates of any sector. AgFF workers also face increased risk of poor mental health, death by suicide, and substance use disorder. The National Institute for Occupational Safety and Health (NIOSH) is committed to addressing a wide range of occupational health and safety hazards affecting people who work in the production, processing, and transportation of AgFF products. This notice of funding opportunity (NOFO) will support up to twelve regional NIOSH Centers for Agriculture, Forestry, and Fishing Safety and Health (AgFF Centers). Each AgFF Center will advance the NIOSH mission and priorities through high-quality research, education, training, and outreach. Key Center activities include: Conducting high-quality, multidisciplinary science, with an emphasis on intervention and implementation research; Advancing AgFF research-to-practice (r2p) by translating scientific discoveries into practical, real-worl Awards up to $2,200,000.
Alzheimer's Disease Programs Initiative (ADPI) - States and Community Grants
Administration for Community Living · Deadline not published
Cooperative agreements under the Alzheimer's Disease Programs Initiative (ADPI): State and Community Grants Notice of Funding Opportunity (NOFO), are intended to support and promote the development and expansion of dementia-capable home and community-based service (HCBS) systems in States and Communities. There are two application options contained in this single NOFO: Grants to States (Option A) and Grants to Communities (Option B). No entity is eligible to apply for both State and Community options and no entity is eligible to hold more than one ADPI State or Community grant at a time. The dementia-capable systems resulting from program activities under either option are expected to provide quality, strengths-based services and supports that help people living with dementia and their caregivers remain independent and safe in their communities. OPTION A: Grants to States Applicants for Option A (36 month cooperative agreements) are the governmental entities within states and territories designated as the state agency for dementia-capability and that have working relationships with their state agencies that enable creating and sustaining a dementia- capable HCBS System. Option A ha Awards range from $850,000 to $1,000,000.
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
National Institutes of Health · Deadline 2027-03-04
This NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR, a re-issue of PAR-24-208, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V. Application Review Information of the funding opportunity are the only changes that have been made. All other aspects of this funding opportunity remain the same.
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases
National Institutes of Health · Deadline not published
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for Exploratory Clinical Trials Grants Program in the mission areas of NIAMS. The goal of the NIAMS clinical trial program is to support research leading to the prevention or reduction of symptoms and improve outcomes and function in patients with rheumatic, musculoskeletal, or skin conditions or diseases. The purpose of the Exploratory Clinical Trials Grants Program is to foster clinical trials that will lead to clinically meaningful improvements in prevention, diagnosis, or treatment of these conditions or diseases. This Exploratory Clinical Trials Grants Program is designed to facilitate the execution of short-term, interventional studies. The Program is intended to support a range of exploratory studies, from proof-of-concept/first in human to Phase I and Phase II clinical trials. Such studies must meet the NIH definition of a clinical trial and be feasible within the time and budget constraints of this NOFO. A high priority is the use of such studies to stimulate the translation of promising research developments fr Awards range from $300,000 to $600,000.
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)
National Institutes of Health · Deadline not published
The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue support for the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care. The program will encourage applications for a clinical coordinating center (CCC) and data coordinating center (DCC) to support the NIH SIREN clinical trial network. Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs
National Institutes of Health · Deadline not published
The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with The National Heart, Lung and Blood Institute (NHLBI), at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN). The program will encourage applications for network clinical enrollment hubs to support the NIH SIREN clinical trial network. The SIREN Network performs clinical trials that impact the care of individuals with a non-stroke neurological and cardiovascular emergency in the pre-hospital or emergency department setting. The goal of SIREN is to improve the outcomes by identifying effective treatments given in the earliest stages of care. Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)
National Institutes of Health · Deadline 2027-03-05
The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding. Awards up to $1,500,000.
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-03-05
The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms.Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.