Funding opportunities
Open and upcoming programs from Canadian funders and US federal grants (Grants.gov). Deadlines first, then rolling intakes.
Strengthening Services to Prevent the Infectious Disease Consequences of Drug Use
Centers for Disease Control - NCHHSTP · Deadline not published
This NOFO aims to strengthen services to prevent the infectious disease consequences of drug use in high impact settings serving people who use drugs (PWUD) through two components. Component 1 will improve service data by conducting a biennial survey of high-impact settings that serve PWUD to document capacity, needs, access, and service gaps. It will also improve timely local data on infectious disease consequences of drug use and the use of infectious disease testing, treatment, and prevention services at high-impact settings through a biennial biobehavioral survey of PWUD. Component 2 will increase support the availability and use of infectious disease testing, treatment and prevention services in high-impact settings serving PWUD. Applicants may apply for Component 1, Component 2, or both. Expected outcomes include enhanced capacity nationally and locally to use data to improve infectious disease testing, treatment and prevention services among PWUD, increased PWUD testing for HBV, HCV, and HIV, increased PWUD with hepatitis C who initiated treatment, and increased PWUD with HIV who engaged in care and treatment. This NOFO is in alignment with CDC priorities.
Medical Scientist Training Program (MSTP)
National Institutes of Health · Deadline not published
The overall goal of the NIH Ruth L. Kirschstein National Research Service Award (NRSA) program is to help ensure that a pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs. In alignment with the goal of the NRSA program, the Medical Scientist Training Program (MSTP) supports the development of well-trained clinician-scientist leaders to address the nation’s biomedical research needs. MSTP will support eligible, domestic organizations to develop and implement effective, evidence-informed approaches to dual-degree training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise and lead to the completion of both a clinical degree (for example, M.D., D.O., D.V.M., D.D.S., Pharm.D., etc.) and a research doctorate degree (Ph.D.). MSTP incorporates didactic, research, mentoring, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation.
Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-05-25
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) is soliciting applications for the establishment of the Management and Data Coordination Unit (MDCU), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC). The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma and conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC-MDCU will provide support towards collaborative efforts such as study design, protocol development, statistical analysis, coordination and data management. Other PCDC-MDCU activities include: coordination and support towards biorepository building; and organizational and logistics support for PCDC activities. Awards up to $500,000.
A Holistic Approach to Study Non-Addictive Natural Products for Pain Management
National Institutes of Health · Deadline not published
The National Center for Complementary and Integrative Health (NCCIH) intends to publish a Notice of Funding Opportunity (NOFO) to support collaborative interdisciplinary research that advances foundational understanding of non-addictive natural products for chronic pain management through a holistic, system-oriented approach. This initiative aligns with the NIH Helping to End Addiction Long-term (HEAL) Initiative by promoting safe, non-addictive, and prevention-oriented strategies for pain relief. Chronic pain affects tens of millions of adults in the United States, contributing to disability, diminished quality of life, and significant healthcare costs. Despite widespread public use of natural products, such as botanicals, dietary supplements, and other naturally derived compounds for pain relief, scientific evidence has not kept pace with demand. Existing research often focuses on single molecular targets or isolated pathways, which fail to capture the complex, multisystem actions of these products. The scope of natural products under this NOFO includes those commonly used by the public as well as those with emerging usage or therapeutic potential. Research is expected to take a
Single Source: Resource Center for the Support for Research Excellence (SuRE) Program
National Institutes of Health · Deadline not published
The Support for Research Excellence (SuRE) program aims to develop and sustain research excellence at resource-limited institutions, many of which disproportionately serve regions of the U.S. that have not historically participated in substantial NIH research, by supporting investigator-initiated research with strong student participation. A SuRE Resource Center has been established to enhance the administrative research infrastructure of SuRE-eligible institutions and to provide services to advise investigators who are interested in applying for a SuRE award. Specifically, the Resource Center: (1) assists institutions with building research capacity, (2) conducts outreach and training to professional staff and faculty at eligible institutions, and (3) collects and reports data relevant to the goals of the program. This is a Forecast for a Single Source that will invite an application from an eligible organization to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application will be peer-reviewed, and only a meritorious application will be considered.
Limited Competition: The NHGRI Analysis, Visualization, and Informatics Lab-space (AnVIL) (U54 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
The National Human Genome Research Institute (NHGRI) intends to issue a Notice of Funding Opportunity (NOFO) to support a limited competition renewal of the Analysis, Visualization, and Informatics Lab-space (AnVIL) program. AnVIL is a secure, cloud-based platform that enables researchers to access, share, and analyze large-scale genomic datasets without relying on local infrastructure. Currently, AnVIL hosts more than 5 petabytes of data from nearly 300,000 research participants, providing a robust environment for reproducible, cloud-native genomic research. The renewed program will continue to advance AnVIL as a community resource grounded in FAIR (Findable, Accessible, Interoperable, and Reusable) principles. Key priorities include enhancing scalability; strengthening interoperability across a federated NIH data ecosystem; and maintaining rigorous security aligned with the Research Authentication Service (RAS) and NIH controlled-access data repositories and access management systems (CADR) requirements (see NOT‑OD‑25‑159). The renewal will also support integration of emerging data types and computational tools, including infrastructure for developing and running AI-based methods
AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
National Institutes of Health · Deadline not published
The National Institute of Mental Health (NIMH) seeks research applications to support the NIMH HIV/AIDS Research Centers (ARC) program, including Developmental Centers (D-ARCs) and full AIDS Research Centers (ARCs). These Research Centers aim to capitalize on the coordinated infrastructure to advance high-impact, interdisciplinary HIV/AIDS research. The ARC program supports innovative research across basic, neuro-HIV, behavioral and social, clinical, translational, implementation science, and data science domains. Centers are expected to foster scientific collaboration, accelerate innovation, and strengthen dissemination of research advances to implementing agencies, affected communities, and other stakeholders. Applications should align with the National HIV/AIDS Strategy, the NIH Office of AIDS Research (OAR) Strategic Plan, and the NIMH Strategic Plan for HIV research. Applications are not being solicited at this time. This notice is being issued to provide potential applicants with ample time to develop strong, collaborative, and responsive project plans. Research teams that have expertise in establishing and sustaining collaborations with academic institutions, community partn Awards up to $1,500,000.
Partnership with Common Fund Data Ecosystem Resources
National Institutes of Health · Deadline not published
The NIH Office of Strategic Coordination (Common Fund) has generated many valuable and widely available datasets. The Common Fund Data Ecosystem is helping to ensure that all Common Fund (CF) data are Findable, Accessible, Interoperable, and Reusable (FAIR). The purpose of this Notice of Funding Opportunity (NOFO) is to announce the availability of funds for projects that involve collaboration between CF programs and a non-CF biomedical data resource or ecosystem to develop resources that will enhance reusability of Common Fund data and help to connect the Common Fund Data Ecosystem with other important biomedical data ecosystems and resources. Examples of other NIH data resources and ecosystems that could be included in this partnership effort include, but are not limited to, the Helping to End Addition Long-term (HEAL) Data Ecosystem, Brain Research Through Advancing Innovation Neurotechnologies (BRAIN) Initiative, Cancer Research Data Commons (CRDC), ImmPort Shared Data, Trans-Omics for Precision Medicine (TOPMed), the National Institute of Child Health and Human Development, the National Library of Medicine research resources, and the Medical Imaging and Data Resource Center (M Awards range from $500,000 to $1,200,000.
Radiation Exposure Screening and Education Program
Health Resources and Services Administration · Deadline not published
This program supports organizations to screen and educate people exposed to radiation related to the mining of uranium and U.S. testing of nuclear weapons. Awards range from $250,000 to $500,000.
Limited Competition: John Lewis NIMHD Research Endowment Program (S21 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
As authorized under section 464z-3(h) of the Public Health Service Act, the purpose of the John Lewis NIMHD Research Endowment Program is to strengthen the research infrastructure and training capacity at eligible institutions of higher education to facilitate health disparities research. Specific strategic objectives include: 1) improving the institutional physical infrastructure and acquisition of research equipment, 2) developing research-enabling technical expertise, 3) expansion of academic science programs relevant to scientific research, and 4) merit-based recruitment of highly accomplished researchers for open faculty positions. The John Lewis NIMHD Research Endowment Program does not directly support research projects. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding. Awards up to $2,000,000.
Undiagnosed Diseases Network (UDN) Clinical Networks of Diagnostic Excellence
National Institutes of Health · Deadline not published
NINDS intends to support multiple clinical Networks of Diagnostic Excellence (NODEs) as part of the next phase of the Undiagnosed Diseases Network (UDN). Unlike prior phases, clinical NODEs are expected to function as geographically distributed regional clinical networks rather than single-site centers. Each clinical NODE would establish and lead a regional network built on existing partnerships with academic medical centers, hospitals, clinics, federally qualified health centers, and other community-based clinical partners to broaden access to specialized diagnostic expertise and extend the reach of the UDN. Clinical NODEs are expected to provide a coordinated, multidisciplinary and participant-centered evaluation of individuals with highly challenging, difficult-to-diagnose conditions. In collaboration with the Network, clinical NODEs will recruit and enroll participants, conduct medical record reviews, make enrollment determinations, communicate review outcomes and recommendations to participants and referring providers, and coordinate the clinical evaluation with local partner sites and referring providers, as appropriate. In addition, clinical NODEs will participate in network
Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center
National Institutes of Health · Deadline not published
NINDS intends to support a new phase of the Undiagnosed Diseases Network (UDN) to advance diagnosis for individuals with previously undiagnosed diseases and undiagnosed diseases research. This phase would emphasize participant and family engagement, provider engagement, use of NIH and non-NIH resources, education, community engagement, research innovation and discovery, and broader implementation of advanced diagnostic approaches. The Network is expected to include a Clinical and Data Coordinating Center (CDCC), clinical Networks of Diagnostic Excellence, the NIH Undiagnosed Diseases Program (UDP), a Diagnostic Research Innovation Center, individuals with lived experience, patient advocacy organizations, NIH, and other stakeholders. NINDS anticipates supporting a CDCC to provide operational oversight and coordination for network activities including recruitment, participant support (e.g., patient navigation services, referring diagnosed participants to potential therapeutic options), protocol and regulatory management, data sharing, innovation in analytics, support for the systematic re-evaluation of unsolved UDN cases, collaboration, training, implementation science research to fa
Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center
National Institutes of Health · Deadline not published
NINDS intends to support a Diagnostic Research Innovation Center (DRIC) for the next phase of the Undiagnosed Diseases Network (UDN). The new Network is expected to include a Clinical and Data Coordinating Center (CDCC), geographically distributed clinical Networks of Diagnostic Excellence (NODEs), the NIH Undiagnosed Diseases Program (UDP), a DRIC, the UDN Foundation, patient advocacy organizations, NIH, and other stakeholders. The DRIC will contribute to the diagnosis of UDN participants, including participating in the systematic re-evaluation of unsolved UDN cases from previous phases of the UDN. The DRIC is expected to test and advance innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions. Working closely with clinical NODEs, the UDP, the CDCC, and other UDN stakeholders, the DRIC will support the generation and testing of diagnostic hypotheses including providing expertise and resources in advanced sequencing and multi-omics, gene function studies in animal and human in vitro models, and the development of non-genetic diagnostic strategies. Collaborating with the Network, the DRIC will contribute to the discovery of novel disease-associate
Limited Competition: Tribal Institutional Review Board Establishment and Enhancement (TIRBEE)
National Institutes of Health · Deadline not published
The Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) Notice of Funding Opportunity will enable federally-recognized Tribes or Tribal Entities to establish or enhance Institutional Review Boards. TIRBEE builds the capacity and infrastructure for biomedical research involving human participants in federally-recognized Tribal communities by expanding their Institutional Review Board review and oversight capabilities. This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.
Research to Improve Rigor, Replicability, and Reproducibility in Biomedical and Behavioral Sciences
National Institutes of Health · Deadline not published
The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with other National Institutes of Health (NIH) Institutes, Centers, and Offices, intends to support research projects that directly improve or evaluate biomedical and behavioral rigor, replicability, and reproducibility. Example projects include, but are not limited to: Assessing the scientific and behavioral impact of improving rigor, replicability, and reproducibility Developing decision-making frameworks to select candidate studies for replication with the highest potential for scientific value or novel insights Measuring replicability, reproducibility, robustness, and generalizability of important research findings to accelerate scientific innovation Applications are not being solicited at this time. This notice is to allow applicants time to develop collaborations and responsive projects.
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
National Institutes of Health · Deadline not published
The National Institute of Neurological Disorders and Stroke (NINDS) is interested in supporting the conduct of scientific research utilizing data from intermediate-size patient population expanded access protocols for ALS ("intermediate expanded access protocol for ALS", see Expanded Access Categories for Drugs (Including Biologics) ). Eligible intermediate expanded access protocols for ALS should: 1) provide access to an investigational drug or biological product for people with ALS, and 2) generate data to support research on the prevention, diagnosis, mitigation, treatment, or cure of ALS. The scientific research goal(s) informed by these data could include the investigational drug's or biological product's effect on biomarkers related to the pathophysiology of ALS or target engagement, the collection of safety or outcome information, such as survival or other significant medical events (e.g., hospitalization or need for ventilatory support), or patient experience data that are not specifically tied to assessing efficacy. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects.
NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
This Notice of Funding Opportunity (NOFO) solicits applications for the NLM Grants for Scholarly Works in Biomedicine and Health program. The program supports the preparation of book-length manuscripts and other scholarly works of academic and/or public health importance to U.S. health professionals, scientists, public health professionals, and other relevant audiences. This NOFO is intended to support scholars in producing critical reviews, analytical syntheses, and other integrative scholarly works that organize, contextualize, and disseminate biomedical and health-related knowledge. Through support for rigorous and integrative scholarship, the G13 program seeks to foster works that deepen understanding of current biomedical and public health challenges and contribute enduring resources for research, education, clinical practice, and public health. Awards range from $10,000 to $80,000.
Coordinating Center for the Claude D. Pepper Older Americans Independence Centers (OAICs)
National Institutes of Health · Deadline not published
The National Institute on Aging intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Coordinating Center (CC) of the Claude D. Pepper Older Americans Independence Centers (OAIC) program. The CC serves as a facilitator for OAIC site interactions and as a conduit for translating OAIC objectives and findings to both scientific and general audiences. The proposed CC must demonstrate an ability to work cooperatively with all OAIC sites and possess sufficient scientific expertise in geriatrics and related areas to serve the national coordination functions of the OAIC program. Applicants should have a demonstrated ability to coordinate multi-site projects. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.
NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-05-26
This Notice of Funding Opportunity Announcement (NOFO) invites R25 applications to support the development and implementation of research education programs for recent baccalaureates from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimers Disease (AD) and Alzheimers Disease and Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive research experiences in the AD/ADRD field with the goal of preparing recent baccalaureates to transition into strong, research-focused advanced degree programs or competitive private sector research careers in AD-related disciplines. Awards up to $400,000.
NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-05-26
This Notice of Funding Opportunity (NOFO) invites R25 applications to support the development and implementation of summer research education programs for high school students, undergraduates, or science teachers from all backgrounds, including those from groups underrepresented in the biomedical and behavioral sciences. It is essential to expand and broaden the skilled Alzheimer's Disease (AD) and Alzheimers Disease Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers. The proposed research education programs will support intensive summer research experiences in the AD/ADRD field with the goal of exposing participants to AD/ADRD research and encourage further study or participation in biomedical and behavioral research. This NOFO does not allow participants to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor. Awards up to $200,000.