Funding opportunities
Open and upcoming programs from Canadian funders and US federal grants (Grants.gov). Deadlines first, then rolling intakes.
FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program
Office of Science · Deadline 2027-09-30
SC hereby announces its continuing interest in receiving applications for support of work in the following program areas: · Advanced Scientific Computing Research · Basic Energy Sciences · Biological and Environmental Research · Fusion Energy Sciences · High Energy and Nuclear Physics · Isotope R&D and Production. On September 3, 1992, DOE published in the Federal Register the Office of Energy Research Financial Assistance Program (now called the Office of Science Financial Assistance Program), 10 C.F.R. part 605, as a Final Rule, which contained a solicitation for this program. Information about submitting applications, eligibility, limitations, evaluation and selection processes and other policies and procedures are specified in 10 C.F.R. part 605. This NOFO is our annual open solicitation that covers all research areas in SC and is open throughout the fiscal year (FY). Any research within SC’s congressionally authorized mission may be proposed under this NOFO. This NOFO will remain open until September 30, 2027, 11:59 PM Eastern Time, or until it is succeeded by another issuance, whichever occurs first. Awards range from $5,000 to $10,000,000.
Home Study and Post-Release Services for Unaccompanied Alien Children
Administration for Children and Families - ORR · Deadline 2027-10-01
This NOFO is modified. Changes are made to Step 1: Review the Opportunity. The Office of Refugee Resettlement (ORR) provides temporary housing and care for children who arrive in the United States alone. These are children who are under 18 years old, don't have legal permission to be in the U.S., and don't have a parent or legal guardian in the U.S. who can take care of them. ORR runs the Home Study and Post-Release Services Program to help these children. Before placing a child with a sponsor, ORR carefully checks potential homes to make sure they're safe and appropriate. After placement, ORR provides ongoing support to help children and their sponsors succeed. This support helps children adjust to living with their sponsor, connect with their community, stay safe and healthy, and navigate the immigration court process. The goal is to make sure children are placed in safe homes and have the support they need to thrive while their immigration cases move forward. Awards range from $1,000,000 to $100,000,000.
Youth Regional Treatment Center Aftercare Program
Indian Health Service · Deadline not published
The goal of the Youth Aftercare cooperative agreement is to help American Indian and Alaska Native (AI/AN) youth achieve and sustain safety, sobriety, and long-term success after discharge from a Youth Regional Treatment Center (YRTC). The program strengthens culturally appropriate, community-based aftercare services by improving care coordination, building partnerships across the continuum of care, and enhancing YRTC capacity to address barriers, support effective case management, and improve outcomes for youth.
Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRC)
National Institutes of Health · Deadline not published
This renewal of the Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRCs) continues a legislatively-mandated Centers of Excellence program, which aims to expand and intensify research on muscular dystrophy. The Centers advance basic, translational, and clinical muscular dystrophy research through interdisciplinary collaboration and shared resources for the research community. They support innovative, center-based projects that would be less effective as stand-alone grants, and provide strong training environments for emerging scientists. The Centers also engage patient and advocacy communities to raise research awareness, encourage participation, and ensure patient-centered perspectives inform study design and conduct. Grant authorities that allow NICHD to forecast this opportunity are as follows: 42 U.S.C. 281 (Sec. 401); 42 USC 283g (Sec. 404E); 42 U.S.C. 285g (Sec. 448); 42 USC 284h (Sec. 409D) Awards up to $1,000,000.
R3PEATS Grassroots Rigor Projects: Individual Metascience and Individual Laboratory Capacity-Building (RP1)
National Institutes of Health · Deadline not published
R3PEATS Grassroots Rigor Projects supports two project types that generate practical tools and shared knowledge to strengthen research practices. Metascience projects develop and evaluate tools, metrics, guidelines, or infrastructure to promote high-quality research practices. Laboratory Capacity-Building projects support labs in adopting new rigor- and replicability-related techniques or processes while tracking and sharing factors that influence research outcomes. This effort is a part of the NIH Common Fund's Rigor, Replicability, & Reproducibility to Promote Excellence, Accuracy, & Translation in Science (R3PEATS) program.
R3PEATS Multi-Team Triangulation: Collaborative Cross-Method Approaches to Scientific Discovery (RM1)
National Institutes of Health · Deadline not published
R3PEATS Multi-Team Triangulation supports coordinated teams to investigate a central biomedical research question through complementary methods, model systems, or populations. Projects must identify signal robustness and sources of biological variability while building replication into the research design. This effort is a part of the NIH Common Fund's Rigor, Replicability, & Reproducibility to Promote Excellence, Accuracy, & Translation in Science (R3PEATS) program.
R3PEATS Rigor Scholar Cohort Awards (K12)
National Institutes of Health · Deadline not published
Rigor Scholar Cohort Awards support early-career researchers to advance expertise in rigorous scientific practices, such as preregistration, blinding, randomization, and transparent dissemination, through multi-institutional collaboration. Working within local and national cohorts, scholars will co-develop procedures and share lessons, building the vital skills needed to champion good scientific practice. This effort is a part of the NIH Common Fund's Rigor, Replicability, & Reproducibility to Promote Excellence, Accuracy, & Translation in Science (R3PEATS) program.
Learning Disabilities Research Centers
National Institutes of Health · Deadline not published
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks to support transdisciplinary research centers to improve outcomes for children and youth at risk for, or diagnosed with, specific learning disabilities (SLDs) impacting mathematics, reading and writing. These centers will focus on improving the identification and classification of SLDs, deepen understanding of their genetic and neurobiological underpinnings, and advance testing of innovative screening and intervention approaches. The proposed centers will use their funded research infrastructure to collaborate with key stakeholders and provide project-based mentorship for the next generation of SLD researchers. Grant authorities that allow the Eunice Kennedy Shriver National Institute of Child Health and Human Development to forecast this opportunity are as follows: 42 U.S.C. 281 (Sec. 401); 42 U.S.C. 285g (Sec. 448); 42 USC 284h (Sec. 409D).
Discovery Gateway to Reproductive Health Innovation
National Institutes of Health · Deadline not published
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks to establish a single Discovery Gateway to Reproductive Health Innovation, a comprehensive knowledgebase designed to advance research on male and female indications such as preeclampsia, endometriosis, preterm birth, infertility, and uterine fibroids. This initiative will expand shared resources and essential infrastructure for the biomedical research community. The Gateway will facilitate integration of existing clinical, pharmacogenomic, and multi-omic data in order to address critical knowledge gaps. By providing open-access, this web-based visualization platform will empower scientists to generate new insights that extend far beyond the scope of individual research efforts. Ultimately, the overarching goal is to catalyze the discovery of new treatments and cures. By identifying potential disease mechanisms, effector genes, biomarkers, and drug targets, the Gateway will drive the development of innovative commercial products and accelerate public-private partnerships. The Discovery Gateway supports multiple implementation recommendations made by the Task Force on Research Specific t
CAPSTONE Centers for Multidisciplinary Research in Child Abuse and Neglect
National Institutes of Health · Deadline not published
This renewal of the CAPSTONE Centers for Child Maltreatment Research initiative will focus on child sexual abuse (CSA), a preventable but understudied public health problem with serious lifelong consequences. CSA is linked to adverse developmental and health outcomes, including chronic gynecological, gastrointestinal, sexual health, and mental health conditions. The renewed Centers are intended to overcome the significant practical, ethical, and methodological challenges in CSA research, addressing critical gaps in CSA research and including a required translation component. The multicomponent and collaborative nature of the P50 mechanism will create national resources for the field supporting innovative, high-quality research including : (1) studies evaluating the efficacy and effectiveness of interventions; (2) longitudinal studies of CSA-related chronic disease outcomes; (3) research on biological embedding and its health implications; and (4) projects that strengthen CSA data infrastructure. Instead of just identifying general risk factors and etiology, the renewed Centers will focus on prevention and translational research to demonstrate measurable public health impact. Grant
BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-10-04
This funding announcement, issued by the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative, seeks transformative, cutting-edge, and innovative research that embraces new technologies, ideas, and approaches to understand brain circuit function and contributions to behavior. It is a component of the BRAIN Initiative Connectivity Across Scales (BRAIN CONNECTS) Program, which aims to lay the scientific foundation for the next generation of neural circuit-based approaches for preventing and treating devastating brain disorders. This Notice of Funding Opportunity (NOFO) supports Specialized Projects to develop current or emerging technologies to generate comprehensive atlases of brain connectivity, with an emphasis on human, non-human primate (NHP), and mouse. Projects using other species are also permitted, if their use is well justified and the goal is to test and validate approaches that can be generalized across species. Applications may address any aspect(s) of brain connectivity and associated data pipelines, including data collection, reconstruction, analysis, integration, dissemination, and interpretation, to enable faster, more precise, and more c
Investigator-Focused Award (Parent R35)
National Institutes of Health · Deadline not published
The National Institutes of Health intends to publish a Parent R35 "Investigator-Focused Award" Notice of Funding Opportunity (NOFO) to fund research programs for investigators at all career stages, including Early Stage Investigators (ESIs). The Parent R35 Investigator-Focused Award is intended to provide support for an investigator's program of research within the mission of the awarding Institute or Center (IC) rather than support for a pre-defined project with specific aims. The R35 is typically expected to be an investigator's primary (or only) source of research funding from the awarding IC. An R35 award gives investigators funding stability and scientific freedom. With R35 support, researchers can pursue ambitious and innovative studies without the pressure of constantly seeking new funding streams. Key benefits include: Providing flexibility to follow the science as it evolves within the awarding IC's mission. Providing stability to take on important, challenging research questions. Allowing recipients to devote sufficient time to research, mentoring, and scientific service, and less time to grant administration. Providing a high potential for scientific breakthroughs by ena
Advanced Technological Education (ATE)
U.S. National Science Foundation · Deadline 2027-10-07
With a focus on two-year Institutions of Higher Education (IHEs), the Advanced Technological Education (ATE) program supports the education of technicians for the high-technology fields that drive our nation's economy. The program involves partnerships between academic institutions (grades 7-12, IHEs), industry, and economic development agencies to promote improvement in the education of science and engineering technicians. It is strongly recommended that projects be faculty-led and required that courses and programs are credit-bearing, although materials developed may also be used for incumbent worker education. Materials may also be adapted and implemented as credit-bearing courses. The ATE program supports curriculum development; professional development of college faculty and secondary school teachers; career pathway development for both students and incumbent workers; and other activities including applied research projects that advance the knowledge base related to technician education. The ATE program encourages partnerships with other entities that may impact technician education. For example, with the National Institute of Standards and Technology (NIST) Manufacturing Exte Awards range from $475,000 to $7,500,000.
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2027-10-08
This Funding Opportunity Announcement (FOA) encourages the submission of applications that propose to advance research in cancer etiology and early detection biomarkers, utilizing the advantages of the unique biorepository resources of the NCI-sponsored Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial. The PLCO Biorepository offers high-quality, prospectively collected, serial pre-diagnostic blood samples from the PLCO screened arm participants, and a onetime collection of buccal cells from the control arm participants. Available data associated with the biospecimens includes demographic, diet, lifestyle, smoking, screening results, and clinical data. This FOA supports a wide range of cancer research including, but not limited to, biochemical and genetic analyses of cancer risk, as well as discovery and validation of early detection biomarkers. The proposed research project must involve use of PLCO biospecimens; additionally, it should also take advantage of the unique characteristics of the PLCO biospecimens. Research projects that do not involve the use of PLCO biospecimens will not be supported under this FOA.
Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)
National Institutes of Health · Deadline 2027-10-08
The Ultra-Rare Gene-Based Therapy (URGenT) network supports Investigational New Drug (IND)-enabling studies and planning activities for First-in-Human (FIH) clinical testing of gene-based or transcript-directed therapeutics, such as oligonucleotides and viral-based gene therapies, for ultra-rare neurological or neuromuscular disorders. The goal of this announcement is to accelerate the development of a promising clinical candidate with robust biological rationale and demonstrated proof of concept (POC) data for the intended approach in a model system relevant to a specified patient population towards an IND filing and the initiation of a clinical trial.
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)
National Institutes of Health · Deadline 2027-10-12
This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scientists to jointly initiate and conduct translational research projects which translate basic research findings into clinical tools for better human health. The scope of this FOA includes a range of activities to encourage translation of basic research findings which will impact the diagnosis, treatment and prevention of communication disorders. Connection to the clinical condition must be clearly established and the outcomes of the grant must have practical clinical impact. Awards up to $500,000.
Mentored Career Transition Award (KT1/R00)
National Institutes of Health · Deadline not published
The biphasic award will provide up to 5 years of support in two phases. The initial, mentored career development phase will provide 1-2 years of support for needed career development to facilitate a timely transition of promising postdoctoral researchers from their mentored postdoctoral research positions to independent, tenure-track or equivalent research-intensive faculty positions. The second phase will provide up to 3 years of independent research support, contingent on satisfactory progress during the first phase and an approved, independent, tenure-track (or equivalent) faculty position.
Mentored Research Scientist Career Development Award (KR1)
National Institutes of Health · Deadline not published
The Mentored Research Scientist Career Development Award provides support for a sustained period of protected time (up to five years) for intensive research career development under the guidance of an experienced mentor. The award is expected to prepare candidates with research doctoral degrees for future research independence.
Mentored Clinician Research Scientist Career Development Award (KC1)
National Institutes of Health · Deadline not published
The Mentored Clinician Research Scientist Career Development Award provides support to clinician research scientists for a sustained period of protected time (up to five years) for intensive research career development under the guidance of an experienced mentor. The award is intended to prepare candidates with clinical doctoral degrees for future research independence.
Established Clinician Investigator Award to Support Mentoring (KS1)
National Institutes of Health · Deadline not published
The Established Clinician Investigator Award to Support Mentoring provides support to established clinician investigators for a sustained period of protected time to provide high-quality mentoring to early-career clinician research scientists.