Funding opportunities
Open and upcoming programs from Canadian funders and US federal grants (Grants.gov). Deadlines first, then rolling intakes.
NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2028-01-07
The NEI supports large-scale clinical vision research projects, including randomized clinical trials and epidemiologic studies on eye/vision conditions. At the time of submission, applications requesting support for these activities are expected to provide detailed information regarding the study rationale, design, analytic methods, protocols and procedures, facilities and environment, organizational structure, and collaborative arrangements. This information is best conveyed in a study protocol and Manual of Procedures (MOP), the development of which represents a costly and time-consuming activity. This clinical research planning grant funding opportunity supports applicants in their planning efforts to conduct collaborative clinical research. The grant may be used to support the development of a study protocol and MOP, as well as to conduct preliminary studies to refine study procedures or document recruitment potential. The grant must not be used to generate data on the effects of a proposed intervention. This NEI NOFO is applicable to both epidemiologic and clinical trial research studies. Awards up to $150,000.
DoW’s Energy, Installations, and Environment Innovation Partners Programs
Washington Headquarters Services · Deadline 2028-01-08
The Office of the Under Secretary of War (OUSW), intends to award non-research cooperative agreements (CA) to help manage and sustain Department of War (DoW) land in the United States. The DoW Strategic Environmental Research and Development Program (SERDP), Environmental Security Technology Certification Program (ESTCP), Readiness and Environmental Protection Integration (REPI) Program, and Legacy Resource Management Program (Legacy Program) fund high priority national and regional natural and cultural resources projects that enhance installation resilience and environmental objectives and support military readiness. Awards up to $100,000,000.
Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2028-01-10
The overall goal of the Stimulating Access to Research in Residency (StARR) program is to provide resident clinicians in training with in-depth research experiences early in their careers, in order to recruit, retain and accelerate independence of a pool of clinician-investigators with both clinical and research experience necessary to perform basic, clinical and/or translational research.
Laboratory Flexible Funding Model (LFFM)
Food and Drug Administration · Deadline 2028-01-11
This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). This is achieved through prioritized sample testing and food defense preparedness in the areas of microbiology, chemistry, and radiochemistry, as well as method development and capacity/capability development projects that support and expand food safety and food defense testing. Awards up to $1,500,000.
Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)
National Institutes of Health · Deadline 2028-01-25
This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting facilities that enable collaborative research and benefit broad research communities at large. The NOFO supports two existing construction programs: the Biomedical Research Facilities (BRF) program and the HIV/AIDS Research Facilities (HRF) program.The BRF program supports the construction or modernization of biomedical research facilities that advance basic, translational, clinical, or behavioral science research in all areas. Intended facilities include shared research spaces, core facilities, biorepositories, or other shared-use resource facilities that serve a broad scientific community with a significant, long-term impact on biomedical research.The HRF program funds the development of HIV/AIDS research or research-supporting resources that the empowered research activities must align with the NIH Office of AIDS Research (OAR) priorities, as outlined at OAR HIV/AIDS Research Priorities, including research focusing on the long-term health consequences of HIV infection.NIH encourages applications from institutions across all geographic regions of the co Awards range from $2,000,000 to $8,000,000.
NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – Regional Coordinating Stroke Centers (RCCs)
National Institutes of Health · Deadline not published
The National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) seek to continue to support the Infrastructure for the NIH Stroke Clinical Trials Network (NIH StrokeNet). The program will encourage applications for network regional clinical enrollment coordinating centers (RCC's) to support the NIH StrokeNet clinical trial network. The NIH StrokeNet conducts clinical trials focused on advancing acute stroke treatment, stroke prevention, and stroke recovery and rehabilitation across the lifespan. Its mission is to improve outcomes for individuals who experience stroke by evaluating promising new therapies for patients with stroke and those at risk for stroke. Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
NIH Stroke Clinical Trials Network (StrokeNet) Infrastructure – National Coordinating Center (NCC) and National Data Management Center (NDMC)
National Institutes of Health · Deadline not published
The National Institute of Neurological Disorders and Stroke (NINDS) at the National Institutes of Health (NIH) seeks to continue support for the infrastructure of the NIH Stroke Clinical Trials Network (NIH StrokeNet). The NIH StrokeNet conducts clinical trials focused on advancing acute stroke treatment, stroke prevention, and stroke recovery and rehabilitation across the lifespan. Its mission is to improve outcomes for individuals who experience stroke by evaluating promising new therapies for patients with stroke and those at risk for stroke. The program will encourage applications for a national clinical coordinating center (NCC) and national data management coordinating center (NDMC) to support the NIH StrokeNet clinical trial network. Applications are not being solicited at this time. This notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive applications for centers.
Limited Competition: Tribal Undergraduate and Graduate Research Training and Leadership Experiences (TURTLE) Program
National Institutes of Health · Deadline not published
The Tribal Undergraduate and Graduate Research Training and Leadership Experiences (TURTLE) Program supports eligible Tribal Entities to develop a pool of students who: Have the skills required to conduct Tribal health research Complete their degrees in a biomedical field, and Transition into careers in the biomedical research workforce. NIGMS will provide support for a phased award to eligible Tribal Entities to develop and implement effective training and mentoring activities for research-oriented individuals earning baccalaureate or doctoral degrees in biomedical research fields at institutions across the United States and its territories. This is a Forecast for a Limited Competition that will invite applications from eligible organizations to apply. Please see the Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered.
Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications (U42 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
This Notice of Funding Opportunity (NOFO) invites applicants to support Testing Centers for Evaluation of Somatic Cell Genome Editing Approaches for Translational Applications. Each center will provide resources and testing services to the growing community, developing new genome editing technologies and conducting preclinical testing based on these technologies for therapeutics for human diseases. The testing centers will work with NIH-funded investigators to assess the efficacy and safety of genome editing and delivery technologies, determine genome editing thresholds for specific diseases associated with minimal off-target effects, and ascertain feasibility parameters in model systems. This NOFO is especially interested in the application of new approach methodologies (NAMs) to complement traditional in vivo models for the purposes described in this announcement. Research Initiative Details The Testing Centers will establish in vivo and in vitro research models applicable to human health and disease, including NAMs and human-biology-based models. The Testing Centers will develop assays and Standard Operating Procedures (SOPs) for evaluating new genome editing technologies. Data Awards range from $580,000 to $900,000.
Limited Competition: Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program
National Institutes of Health · Deadline not published
The Biomedical Research Environment & Sponsored Programs Administration Development (BRE-SPAD) Program supports resource-limited institutions to develop and strengthen their capacity to conduct rigorous and reproducible biomedical research. Eligible organizations are expected to propose plans based on identified needs in one or more of the following areas: biomedical research environment, sponsored programs administration and a post-award pilot research project program. By supporting research capacity building at resource-limited institutions, the BRE-SPAD program will expand and strengthen the pool of faculty and trainees conducting rigorous biomedical research, and the organizational settings where NIH-funded research is performed. This is a Forecast for a Limited Competition that will invite applications from eligible organizations to apply. Please see the Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered for funding.
Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)
National Institutes of Health · Deadline 2028-01-28
The purpose of this announcement is to encourage investigators to pursue translational activities and clinical feasibility studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent clinical feasibility study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This FOA is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress. Participants in Blueprint MedTech receive funding for all activities
Commercial Fishing Occupational Safety Research Cooperative Agreement (U01)
Centers for Disease Control and Prevention - ERA · Deadline 2028-01-31
The Fishing Safety Research Grant Program established by The Coast Guard Authorization Act of 2010 (P.L. 111-281), as amended by the Howard Coble Coast Guard and Maritime Transportation Act of 2014 (P.L. 113-281), is intended to provide funding to individuals in academia, members of non-profit organizations and businesses involved in fishing and maritime matters, and other persons with expertise in commercial fishing safety. The funding will be used to support research on improving the occupational safety of workers in the commercial fishing industry. This includes: improving vessel design; developing and improving emergency and survival equipment; enhancing vessel monitoring systems; improving communication devices, de-icing technology, and severe weather detection. In order to support and administer the grant program, the Coast Guard and NIOSH signed a Memorandum of Understanding on May 17, 2018. While the Coast Guard, along with the Occupational Safety and Health Administration (OSHA), provides regulatory oversight for safety and health matters within the commercial fishing industry, NIOSH is an agency operating under the Centers for Disease Control and Prevention (CDC) with the Awards range from $150,000 to $975,000.
Commercial Fishing Occupational Safety Training Project Grants (T03)
Centers for Disease Control and Prevention - ERA · Deadline 2028-01-31
The goal of the training grant program is to enhance the quality and availability of safety training for United States commercial fishermen. Availability includes the frequency, geographic considerations, channels or partners of dissemination, culturally and/or educational appropriate training material, and other characteristics of a successful training program. As a result, the Coast Guard and NIOSH invite applications to support the development and implementation of training and education programs that: develop and deliver training which addresses the needs of commercial fishermen in the United States provide qualified marine safety instructors, or otherwise accepted by the National Maritime Center instructors and faculty to conduct the training evaluate the effectiveness and impact of the training program on reducing injuries among fishermen coordinate with existing training programs and partnerships with industry fishermen, and agencies conform to 46 U.S.C. § 4502 (i) Safety Standards for commercial fishing safety training In order to support and administer the grant program, the Coast Guard and NIOSH signed a Memorandum of Understanding on May 17, 2018. While the Coast Guard, Awards range from $250,000 to $975,000.
Fiscal Year 2026 Flood Mitigation Assistance Swift Current
Department of Homeland Security - FEMA · Deadline 2028-01-31
FMA Swift Current aims to better align the delivery of FMA flood mitigation funding to the disaster survivor experience. The FMA grant program makes federal funds available to states, U.S. territories, federally recognized Indian/Native American Tribal Governments, and local governments to reduce or eliminate the risk of repetitive flood damage to buildings and structures insured under the National Flood Insurance Program (NFIP), and within NFIP-participating communities. FMA funds a variety of flood mitigation activities that are designed to reduce flood risk to NFIP policyholders in an effort to reduce the NFIP’s financial exposure.
ancient DNA for Modern Genomics (aDMG) Research Projects (U01 Clinical Trials Not Allowed)
National Institutes of Health · Deadline not published
The National Human Genome Research Institute (NHGRI) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to establish an ancient DNA for Modern Genomics (aDMG) program. The goal of aDMG is to establish an ethical resource of ancient and historical human DNA (aDNA) data to advance studies about contemporary human traits and biology. This NOFO aims to solicit applications that will leverage existing and newly generated aDNA data from this consortium to advance the biological and epidemiological understanding of modern human diseases and health-related traits by integrating aDNA with modern human and other species’ data. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. Investigators with expertise and insights into this area of ancient DNA and population genomics are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in DNA sequencing methods and technology, computational genomics and data science, human evolution, and ancient human populations will be encou
Technology Development Program
National Institutes of Health · Deadline not published
This Technology Development funding opportunity will support technology research projects from proof-of-concept through prototype development. The program will prioritize innovation over feasibility. To maximize impact on future biomedical research, projects must focus on technological advances and should not include tests of biological hypotheses or biomedical aims.
NDEP STEM Open NFO
Washington Headquarters Services · Deadline 2028-02-08
This is an open NFO, applicants may apply to this posting or subsequent amendments for specific STEM activities. See the Related Documents tab for the full NFO, and amendments announcing new funding opportunities. The Department of War (DoW) Office of the Under Secretary of War for Research and Engineering (OUSW(R&E)) seeks innovative applications on mechanisms to implement and research the effectiveness of STEM education, outreach, and/or workforce initiative programs, here onto referred as STEM activities. In response to this NFO, the Department intends to release amendments and solicitations, such as Industry Days, Opportunity Days, etc., detailing funding opportunities through award(s) in STEM activities. These activities include, but are not limited to: STEM Education and Outreach Support for STEM Education at Two-Year Institutions/Community Colleges (2YI/CCs) Manufacturing Engineering Education Program Education and Workforce Development aligned to the DoW Critical Technology Areas STEM Scholarship Programs Strategic Partnerships Program Evaluations, Assessments, Data Analytics and Visualizations Other NDEP Congressional Initiatives and Programs As funding becomes available, Awards range from $100,000 to $10,000,000.
Reissue of RFA-FD-22-001 - Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases (R01 Clinical Trials Optional)
Food and Drug Administration · Deadline 2028-02-08
The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs. Through the support of natural history studies with high quality and interpretable data elements, FDA expects to address critical knowledge gaps, remove major barriers to progress in the field, exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and facilitate rare disease product development. Awards up to $600,000.
WaterSMART Cooperative Watershed Management Program
Bureau of Reclamation · Deadline 2028-02-15
The WaterSMART Cooperative Watershed Management Program funding opportunity invites eligible entities to apply for funding to develop local solutions to address their water management needs. This opportunity provides funding for watershed group development, restoration planning, and watershed management project planning and design. By providing this funding, Reclamation promotes water reliability and cooperation between stakeholders to reduce conflict, facilitate solutions to complex water issues, and stretch limited water supplies.The WaterSMART Cooperative Watershed Management Program demonstrably advances Trump administration priorities, such as those identified in Presidential Executive Order 14154 (January 20, 2025): Unleashing American Energy (E.O. 14154) and Secretarial Order 3418, and aligns with other priorities and requirements, such as those identified in Presidential Executive Order 14332 (August 7, 2025): Improving Oversight in Federal Grantmaking (E.O. 14332). Awards range from $50,000 to $300,000.
Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)
National Institutes of Health · Deadline not published
This notice of funding opportunity (NOFO) encourages innovative research to develop, characterize, improve or preserve research models and model related biological materials, and to develop or improve technologies, including new approach methodologies (NAMs), for studies relevant to human health and diseases. This NOFO also seeks projects aimed at improving the identification and control of factors that could confound or interfere with the use of research models in biomedical research. The proposed project must have broad applicability to multiple NIH Institutes or Centers (ICs) to align with the NIH-wide mission of the Office of Research Infrastructure Programs (ORIP). The proposed studies must include research model(s) or NAM(s) and must explore multiple body systems or multiple categories of diseases affecting multiple body systems. Applications that develop models focused on a specific disease, a narrow area of research, or a single body system, or propose studies primarily relevant to a single NIH IC will be considered not acceptable to this NOFO. Awards range from $190,000 to $500,000.